Methodology and indications of H2-breath testing in gastrointestinal diseases: the Rome Consensus Conference.
نویسندگان
چکیده
BACKGROUND Breath tests represent a valid and non-invasive diagnostic tool in many gastroenterological conditions. The rationale of hydrogen-breath tests is based on the concept that part of the gas produced by colonic bacterial fermentation diffuses into the blood and is excreted by breath, where it can be quantified easily. There are many differences in the methodology, and the tests are increasingly popular. AIM The Rome Consensus Conference was convened to offer recommendations for clinical practice about the indications and methods of H2-breath testing in gastrointestinal diseases. METHODS Experts were selected on the basis of a proven knowledge/expertise in H2-breath testing and divided into Working Groups (methodology; sugar malabsorption; small intestine bacterial overgrowth; oro-coecal transit time and other gas-related syndromes). They performed a systematic review of the literature, and then formulated statements on the basis of the scientific evidence, which were debated and voted by a multidisciplinary Jury. Recommendations were then modified on the basis of the decisions of the Jury by the members of the Expert Group. RESULTS AND CONCLUSIONS The final statements, graded according to the level of evidence and strength of recommendation, are presented in this document; they identify the indications for the use of H2-breath testing in the clinical practice and methods to be used for performing the tests.
منابع مشابه
Unclear Abdominal Discomfort: Pivotal Role of Carbohydrate Malabsorption
BACKGROUND/AIMS Carbohydrate malabsorption is frequent in patients with functional gastrointestinal disorders and in healthy volunteers and can cause gastrointestinal symptoms mimicking irritable bowel syndrome (IBS). The aim of this study was to investigate the prevalence of symptomatic lactose and fructose malabsorption in a large population of patients with IBS-like symptoms based on Rome II...
متن کاملCLINICAL GASTROENTEROLOGY AND HEPATOLOGY 2007;5:959–963 bility of the Normal Human Small Intestine to Absorb Fructose: valuation by Breath Testing
p ackground & Aims: Fructose consumption is increasng, and its malabsorption causes common gastrointestinal ymptoms. Because its absorption capacity is poorly undertood, there is no standard method of assessing fructose bsorption. We performed a dose-response study of frucose absorption in healthy subjects to develop a breath test o distinguish normal from abnormal fructose absorption apacity. ...
متن کاملEvaluation of small intestine bacterial overgrowth in patients with functional dyspepsia through H2 breath test.
CONTEXT Functional dyspepsia is a condition in which symptoms are not related to organic underlying disease; its pathogenesis is not well known. The small intestinal bacterial overgrowth (SIBO) is characterized by the increase in the number and/or type of colonic bacteria in the upper gastrointestinal tract. The hypothesis of SIBO being associated to functional dyspepsia must be considered, sin...
متن کاملAbdominal pain-related functional gastrointestinal disorders based on Rome III criteria in a pediatric gastroenterology clinic
Background: Functional gastrointestinal disorders (FGIDs) entail several distinct conditions that collectively account for a sizeable proportion of patients complaining of abdominal pain. Physicians’ awareness is fundamental to avoid unnecessary evaluations and to alleviate stress-related problems. This study aimed to assess the relative frequencies of FGIDs and related categories in a se...
متن کاملFructose and lactose intolerance and malabsorption testing: the relationship with symptoms in functional gastrointestinal disorders
BACKGROUND The association of fructose and lactose intolerance and malabsorption with the symptoms of different functional gastrointestinal disorders (FGID) remains unclear. AIM To investigate the prevalence of fructose and lactose intolerance (symptom induction) and malabsorption and their association with clinical gastrointestinal (GI) as well as non-GI symptoms in FGID and the outcome of d...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Alimentary pharmacology & therapeutics
دوره 29 Suppl 1 شماره
صفحات -
تاریخ انتشار 2009